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CX-4945 and TBB inhibit CK2 [28], which phosphorylates a variety of proteins that regulate DDR, circadian rhythms, cell survival, senescence, and apoptosis

doi: 10.1016/j.cub.2017.09.019

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Additionally, peptide DSIP has been shown to interact with the hypothalamic-pituitary-adrenal (HPA) axis, which plays a crucial role in stress adaptation and immune function

However, the majority of the (pro)drugs and nanocarriers has not reached clinical trials

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