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Distant metastasis: If the cancer has spread to parts of the body away from the original tumor at the time of diagnosis, theres a higher chance of the tumor returning and a 14 times higher risk of death

However, VEGF pathway activation in the context of normal tissue repair differs substantially from VEGF activity in established tumors

Stuttgart u.a.: Thieme

doi:10.3390/ijms22010181

E.CutilliJ.PilieroL

AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway Sun X, Deng Y, Fu X, et al