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The nanoparticles were prepared using an antisolvent precipitation method, producing spherical nanoparticles with an average size of 88.36 1.67 nm, a PDI of 0.047 0.007, and an encapsulation efficiency of 89.52 1.74%, coupled with a sustained-release profile where 93% of puerarin released over 48 h
Typical cycle: 812 weeks
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Pro-inflammatory adipokines (e.g., leptin, resistin) and adipose-derived exosomes (carrying miRNAs like miR-3074-5p) create a chronic inflammatory joint microenvironment by polarizing synovial macrophages toward an M1 phenotype and inhibiting anti-inflammatory adiponectin (1618)
Of particularly important finding in the present study was that the neurological function was significantly preserved in DPP4 D-HS and F344 HS + Sita animals than in F344 HS counterparts by days 3, 7 and 14 after AHS
High-dose L-carnitine
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