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Controlled loading through the healing tissue often improves collagen organization and final tissue strength

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however, delayed inhibition after the inflammatory peak preserves normal healing

In conclusion, this study reviews the significant role of acetylation and deacetylation in renal physiology and pathology and focuses on introducing the roles and mechanisms of deacetylases HDACs and SIRTs, which regulate the deacetylation process in renal physiology and pathology

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