Clinical trials used doses as high as 1 mg per day without safety concerns, but 300 mcg is the most commonly referenced dose in peptide medicine literature and in the investigational protocols that have been published since the formal trials concluded
"Ever since it was discovered, (B12) has been given to cure all kinds of things but, if you have an adequate level, there are no good studies to support that it helps with anything," she said
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High oral bioavailability Caco-2 cell assays showed excellent passive and active membrane transport with no detectable efflux (Neelakantan et al., 2018)
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Accessed January 14, 2025