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This approach provides patients with consistent availability regardless of Novo Nordisk manufacturing constraints

doi: 10.1016/j.jasms.2007.09.015

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Summary Takeaway Messages Despite the ability of GLP-1s to produce significant weight reduction and related health benefits, challenges such as GI side effects, risk of nutrient inadequacies, loss of muscle and bone mass, high costs, frequent discontinuation, and weight regain limit the use of these drugs for long-term success in individuals and populations

E61.1 captures the first two stages