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2 The development of and approval of new antihyperglycemic medications has favored the use of different pharmacological families with remarkable properties for the management of additional comorbidities such as renal disease, cardiovascular disease, and non-alcoholic fatty liver disease, that are highly prevalent in this subset

GLP-1 Market Segmentation By Type of Molecule Outlook (Revenue, USD Billion, 20212034) Biologics Small Molecules By Active Compound Used Outlook (Revenue, USD Billion, 20212034) Dulaglutide Liraglutide Orforglipron Retatrutide Semaglutide Survodutide Tirzepatide Other Active Compounds By Type of GLP-1 Agonist Drugs Outlook (Revenue, USD Billion, 20212034) Long-acting GLP-1 Agonist Short-acting GLP-1 Agonist By Route of Administration Outlook (Revenue, USD Billion, 20212034) Oral Parenteral By Target Indication Outlook (Revenue, USD Billion, 20212034) Alzheimers Disease Non-Alcoholic Steatohepatitis Obesity Sleep Apnea Type 2 Diabetes By Regional Outlook (Revenue, USD Billion, 20212034) North America U.S

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The review also highlighted preclinical evidence that GLP-1 receptor activation can counteract reactive oxygen species and mitigate oxidative cytotoxicityprocesses that accelerate cellular injury across multiple neurodegenerative pathways