Do not switch on your own your prescribing physician should manage the changeover to avoid dosing errors or a gap in treatment
When to Contact Your Healthcare Provider Call your healthcare provider if: Diarrhea lasts longer than one week without improvement You have more than six watery stools per day You cannot stay hydrated or feel lightheaded Over-the-counter oral rehydration drinks are not helping You notice any red-flag symptoms mentioned above Your provider might review your dose schedule , check for other medications that can upset your stomach, or order blood tests to check your hydration and electrolytes
Additionally, its worth repeating that semaglutide is not approved for or effective in managing type 1 diabetes
During the Consultation : Prepare to speak with your doctor about your symptoms, medical history, and any relevant lifestyle factors
Side effects of Ozempic, like nausea and vomiting, could impact the absorption of oral contraceptives
Second Natures peer-reviewed study published in JMIR Formative Research (2025) compared both medications within our programme: 3 Tirzepatide (Mounjaro) cohort (209 people): 22.1% average weight loss at 12 months 95.2% achieved at least 10% weight loss 83.7% achieved at least 15% weight loss Semaglutide (Wegovy) cohort (130 people): 17.1% average weight loss at 12 months 83.1% achieved at least 10% weight loss 56.2% achieved at least 15% weight loss Both cohorts exceeded clinical trial results, suggesting that comprehensive behavioural support enhances outcomes regardless of which medication you use