Heat shock proteins: dynamic biomolecules to counter plant biotic and abiotic stresses
Lipidomic analysis in TfamAKO mice reveals elevated free FAs, and spatial analysis in 5FAD mice links LD accumulation to A pathology-rich regions, where astrocytes show impaired FAO and mitochondrial FA trafficking (45)
References lvarez-Lario, B
This complex binds to hypoxia response elements in the promoter regions of target genes, regulating the transcription of genes involved in metabolic adaptation and glycolysis (Lee S
GLP-1 drug therapy helps in multiple ways: Improves insulin production when blood sugar is high Reduces the release of glucagon, a hormone that increases blood sugar Slows down gastric emptying, making you feel full for longer Reduces appetite, leading to fewer calorie intakes These combined effects make GLP-1 agonists powerful tools for diabetes weight control
Beyond glucose-lowering, tirzepatide achieved remarkable and sustained weight loss, with mean reductions exceeding 20% in non-diabetic adults with obesity after 72 weeks
