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Tripathi et al
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The majority of T2D management is in primary care, where clinicians (medical, nursing and pharmacist staff) play an important role in addressing patient needs and achieving treatment goals
PI3K activates protein kinase B (Akt), which inactivates several important substrate proteins, such as glycogen synthase kinase 3 (GSK-3) 18 and forkhead box O, 19 and activates mammalian target of rapamycin (mTOR)
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