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Patients taking the 10mg dose typically excrete about 70 grams of glucose per day this way, which accounts for the blood sugar reduction and modest weight loss seen in clinical trials

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When taken in tablet or capsule form, it is then typically inactivated by the liver

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Serpa Daz D, Llanos Florez CA, Uribe RS (2024) Glycemic Control and Body Weight Reduction with Once Weekly Semaglutide in Colombian Adults with Type 2 Diabetes: Findings from the COLIBRI Study Diabetes