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Interestingly, similar genetic alterations, namely mutations of the FGFR3/PI3K pathway, have been demonstrated in both actinic lentigo and adenoid seborrheic keratosis, suggesting a possible relationship at molecular level

One explanation for this finding is that Pelo stability is disrupted in the absence of Hbs1, and the destabilisation of its tertiary structure leads to the premature degradation of the protein in vivo

10.2147/DDDT.S58459 98 LeaM

While rare, a larger hematoma may need evaluation

Silver nitrate (AgNO 3 ) was taken as the metal precursor while Ag-NPs were prepared in the over reaction time