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The increase in the value of the inflammation marker CRP was borderline significant from time zero to 48 hours after the intervention in the group with acute pancreatitis

So the drug didnt demonstrate it lowers cardiovascular risk

The expected decrease in HbA1c is 0.71%,46 and sustained efficacy has been demonstrated in studies with up to fouryears of follow-up.47 Since their mechanism of action is insulin-independent, the SGLT2 inhibitors are effective in all stages of DM2 and do not cause hypoglycemia when administered in monotherapy

6 Pistone G, Marino AD, Leotta C, et al

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