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However, as common obesity is a state of leptin resistance, the exogenous administration of even exceedingly high doses of leptin has proven relatively ineffective at reducing body weight [14-16]

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Anti-apoptotic protection of dermal papilla cells AHK-Cu protected DPCs from programmed cell death through multiple molecular pathways: Bcl-2/Bax rebalancing: Bcl-2 (an anti-apoptotic protein dominant during the telogen-to-anagen transition) was upregulated, while Bax (a pro-apoptotic protein) was downregulated