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Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs (e.g., carbonic anhydrase inhibitors such as topiramate), age 65 years old or greater, having a radiological study with contrast, surgery and other procedures, hypoxic states (e.g., acute congestive heart failure), excessive alcohol intake, and hepatic impairment

Figure 3 Interaction partner analysis of GPXs The interactome network was constructed for 10 putative interactors of Arabidopsis cytosolic GPX2, using Cytoscape with STRING data (Figure 4)

It plays a crucial role in the production of energy by transporting fatty acids into your cells' mitochondria (1, 2, 3)

21 Keeping a simple food and symptom diary for a short period can be a valuable tool to identify personal triggers and discover which management strategies are most effective for them

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