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A blood test is used to diagnose vitamin B12 deficiency

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FDA briefing document US Food and Drug Administration

The vitamin is absorbed in two ways: Active through a special transport molecule (intrinsic factor) saturated at approximately 1.5g per dose/meal Passive through vitamin B12 that passes through the intestinal wall without a transport molecule maximum 1% of the supplied dosage The real intake is calculated through the combination of these two mechanisms

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