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GLP-1 Uses Under Investigation GLP-1s for Addiction Soon after GLP-1s became available for diabetes and then weight loss, users began anecdotally reporting fewer cravings for things like cigarettes and alcohol and less desire to engage in compulsive activities like shopping or gambling

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Thats why staying in regular contact with your clinician even once youve stopped a GLP-1 is important

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This dual mechanism means tirzepatide engages pathways that were not being stimulated by semaglutide, providing a form of receptor novelty