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Studies have shown that tamoxifen resistance is associated with IGFBP-1 accumulation and that the overexpression of IGFBP-1 promotes tamoxifen resistance in breast cancer cells by activating the ERK pathway, which can be reversed by knocking down IGFBP-1 (134)
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Some patients find that nutritional supplement drinks can help maintain adequate nutrition when solid food intake becomes challenging
2019, doi: 10.3389/fendo.2019.00389
The FAQ also notes that anti-nausea medications such as ondansetron (generic Zofran) are helpful in mitigating nausea
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