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NAPQI is being conjugated at the rate at which new GSH is being synthesized, which keeps the concentration of GSH from rising

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Telmisartan modulates mitochondrial function in vascular smooth muscle cells

This keeps metabolism active and prevents the caloric creep that causes plateaus

Individuals with insulin resistance, elevated inflammation, or dysregulated adipose tissue may have blunted beta-3 receptor signaling that limits the peptides effectiveness

doi: 10.1007/s00401-024-02712-2 156 JarettL.SealsJ