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Choline prevents cholesterol buildup

2015 Sep 3;6:245

Current evidence supports that the novel antidiabetic drugs exert cardioprotective effects and reduce the comorbidity in DM patients with HFpEF

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Accumulated AGEs bind to membrane receptors on endothelial cells and promote the onset of tissue damage and the activation of the proinflammatory pathway that involves the NFB transcription factor responsible for regulating the expression of other inflammatory cytokines (Figure 4) [37]