On one hand, GLP-1RA could reduce the proliferation of effector T cells, promote the generation and function of Treg cells
C A basal plus correction insulin regimen is the preferred treatment for patients with poor oral intake or who are taking nothing by mouth
Next, side effects
Earlier, Pfizer acquired Metsera in a ~$10B deal, bringing: MET-097i - a weekly/monthly injectable GLP-1 with strong Phase 2 signals MET-233i - an amylin analog for combination boosting Two oral GLP-1s entering first-in-human studies Combined with Pfizers own oral GIPR antagonist (PF-07976016), this forms a rebuilt, multi-mechanism cardiometabolic pipeline
Key agents include albiglutide, dulaglutide, exenatide, liraglutide, and semaglutide
Perioperative anesthesia management of GLP-1 receptor agonists: a systematic review of potential risks