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This benefit is also supported by trials such as LEADER, SUSTAIN-6, and EXSCEL, in which the reduction in MACE was significant among those with established ASCVD

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Plum-Mrschel, Pharmacokinetic properties of a once-weekly fixed-ratio combination of Insulin Icodec and Semaglutide compared with separate administration of each component in individuals with type 2 diabetes mellitus

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Genes from the three or four most significantly enriched pathways from all comparisons were ranked according to P value (adjusted) and subsequently displayed on a heatmap with log(fold change) represented by colour