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Information sources and search The literature was explored using the MEDLINE (via PubMed) and Web of Science databases, including all articles published from the inception up February 2020

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The results of another randomized trial in 39 patients with Alzheimers disease suggested that supplementation with fish oil concentrate (high in omega-3 fatty acids) with or without lipoic acid (600 mg/day) for one year could delay the progression in cognitive and functional impairments assessed by the Instrumental Activities of Daily Living (IADL) scoring system compared to placebo (104)