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RA patients fulfilled the ACR-EULAR 2010 criteria (38) and had to be positive for anti-CCP2 antibodies

Oral BPC157 has been evaluated in models of gastric ulcers, colitis, and gut permeability, where it has shown protective and prohealing effects on the mucosal lining

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Oral formulations have been investigated for their potential effects on the stomach, intestines, and gastrointestinal lining while also being evaluated for broader systemic activity