Based on the results of previous studies, it seems that L-carnitine needs a longer duration of use to have significant effects on glycemic indices-related markers in diabetic patients ( Subgroup analysis of our findings showed that trial duration, intervention dose, and BMI status significantly affect the insulin level, as well as, it was shown that trial duration, intervention dose, obesity, and health status have a significant effect on the HOMA-IR levels
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When patients discontinue Wegovy, research shows approximately 5070% of lost weight returns within one year because appetite hormones and metabolic rate revert to pre-treatment levels
Acknowledgements We are grateful to Sofie Lsch and Ines Otte for technical assistance
Limitations It should be noted that the present cohort represents a late-onset Swedish TTR-V30M population, which may differ from populations in other endemic regions
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