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Horm Res 1991 36(suppl):73 [PubMed: 1806490] 55

& Holmgren, A

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When combined with a GHRH analog such as Sermorelin, this interaction has been examined for its potential to influence signaling amplitude and temporal release patterns

Specific deletion of igf-1 in the osteocyte using dentin matrix acidic phosphoprotein 1 (DMP-1) promoter driven Cre recombinase highlights the role of IGF-1 in regulating bone turnover during developmental bone growth as demonstrated by the reduced serum levels of the bone formation marker, procollagen type I N-terminal propeptide (PINP) and the bone resorption marker, c-telopeptide (CTx) and decreases in osteoclast surface and osteoclast numbers