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Heidet 2009)

Mechanistically, STING was shown to directly interact with YY1, inhibiting its nuclear translocation and consequently promoting transcription of lipocalin-2 (LCN2)

As the only de novo synthesised steroid, cholesterol is a substrate for the synthesis of steroid hormones, bile acids, and cardiotonic steroids (CTS)

However, in rare instances, the pigmentation may become so dark that it obscures the underlying lichenoid pathology

Central Nervous System Pathways: Cag acts centrally through the brain rather than purely on peripheral tissues