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Species can differ substantially in absorption, transport, hepatic metabolism, renal handling and off-target effects
If a GLP-1 is available and appropriate, it can be an effective option to try prior to surgery. Other times, GLP-1s are recommended for people with extremely elevated BMIs to help them lose weight in preparation for weight loss to surgery, which can lead to a safer surgery
Matsubara E, Bryant-Thomas T, Pacheco Quinto J, Henry TL, Poeggeler B, et al
Agence nationale de scurit du mdicament et des produits de sant (ANSM)
Patients on GLP-1 medications face different dietary challenges
It was also found to be active in burn models
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