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Wadden T et al

Technical Specifications Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2 Molecular Weight: 711.9 g/mol Storage: Store at -20C (lyophilized) or 2C8C (reconstituted)

Despite evidence indicating incr levels of free carnitine and carnitine metabolites in the blood and urine following an oral dose, no significant change in RBC carnitine levels was noted in healthy subjects, suggesting either a slow repletion of tissue stores of carnitine following an oral dose or a low capability to transport carnitine into tissues under normal conditions

Regulation of the glutamate transporter EAAT3 by mammalian target of rapamycin mTOR

444 For example, OT administration increases the connectivity of brain regions critical for processing socioemotional information, such as the NAc, amygdala and PFC

These changes are temporary and typically resolve within 2-3 months of weight stabilization