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Lipid metabolism The effects of NRF2 on lipid metabolism are less well characterized

NO can play either a positive or negative regulatory role in the ETH network

Given its dose-dependent effectiveness and safety, NAC is a strong candidate for repurposing as a clinical treatment for liver disease (61)

Moreover, HTyr and other olive polyphenols are capable of increasing ATP levels in a cellular model of AD (SH-SY5Y-APP695 cells), while the olive-derived secoiridoid ligstroside also improves mitochondrial respiration and biogenesis, extending the lifespan in aged mice and improving the cognitive function [124]