Bruising at the injection site affects up to 30% of people starting GLP-1 medications like semaglutide, though it typically resolves within days
But less food often means less nutrient intake, and when you combine reduced intake with altered gastric motility and absorption patterns, you create conditions for meaningful depletion
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He was surprised that although the [very low-calorie diet] resulted in greater reductions in weight, fat mass, and insulin resistance, it did not appear to enhance beta cell function. The authors suggest that this is because the participants had been living with type 2 diabetes for a long time