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The combined effect of LPS and IFN revealed the largest increase in endothelial permeability and there was a significant loss of the glycocalyx, accompanied by a further decrease in heparan sulfate proteoglycan 2

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We are studying resistance to estrogen induced apoptosis because clinical experience shows us that only 30% of patients respond to estrogen induced apoptosis once exhaustive antihormonal therapy occurs [9]

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