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Gut microbiome influences efficacy of PD-1 based immunotherapy against epithelial tumors

10.1123/ijsnem.10.4.415 17 BrattonM

doi: 10.1038/ng.2653

So far, the FDA has primarily approved treatments for AD that focus on compensating for cholinergic neuron loss using drugs such as inhibitors for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), including medications like tacrine, donepezil, rivastigmine, and galantamine, as well as the glutamatergic drug memantine, which functions as an N-methyl-D-aspartate (NMDA) receptor antagonist (Albertini et al

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Moreover, Sirt2 enhances macrophage activation in response to M.tb infection