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More than just a pricing issue, this dispute reveals how innovation, access, and commercial strategy are shaping the future of metabolic disease treatment

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doi:10.1038/nn.2146

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While PIONEER 6 demonstrated cardiovascular safety (non-inferiority), and the SOUL trial reported significant reductions in MACE, the oral formulation does not yet carry a formal FDA indication for cardiovascular risk reduction in high-risk adults with type 2 diabetes