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Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

This decline weakens the bodys defence system, leading to oxidative stress and disrupted melanin production

[DOI] [PubMed] [Google Scholar] 51.Tang M., Zhang X., Fei W., Xin Y., Zhang M., Yao Y., Zhao Y., Zheng C., Sun D

Primary Mechanism: Selective NNMT Inhibition and NAD+ Restoration

Next, through RNA-seq and MeRIP-seq analyses, SLC7A11 was identified as a downstream target of FTO-mediated m6A modification, which was further confirmed by luciferase and western blot analysis in control and FTO over-expression/knockout PTC cells

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