are inventors on a patent application covering GLP-1 analogues described here
However, we cannot rule out the possibility that the absence of gld-1 and gld-2 activity may mask GLP-1 signaling dependent changes in RNA levels
And GLP-1 peptide drugs like semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound) have undergone extensive testing in clinical trials to become FDA-approved drugs for obesity and type 2 diabetes
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But how glutathione actually enters mitochondria was unknown until 2021, when Birsoy and his team discovered that a transporter protein called SLC25A39 delivers the package
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