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Das Risiko fr bedeutsame unerwnschte kardiovaskulre Ereignisse (MACE, Major Adverse Cardiovascular Events) wurde ber bis zu 5 Jahren um 20 % gegenber Placebobehandlung gesenkt

Visualization of arrestin recruitment by a G-protein-coupled receptor

Monitoring: urine output, electrolytes (especially potassium), weight, and signs of dehydration

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Many patients transition to a maintenance schedule of one shot every 2 to 4 weeks rather than stopping completely

Animals (Scientific Procedures) Act, 1986, and associated guidelines, as well as the EU Directive 2010/63/EU on the protection of animals used for scientific purposes