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doi: 10.1113/jphysiol.2010.201343 Wall BT1, Stephens FB, Constantin-Teodosiu D, Marimuthu K, Macdonald IA, Greenhaff PL

Biomarkers like AMH, antral follicle count, and sperm DNA fragmentation may guide decisions

Others use it more regularly within limits

Thus, oral administration of a peptide therapeutic represents a significant advance in medicine, but is challenged by gastrointestinal instability and ineffective uptake into the circulation