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Footnotes [1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic

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9,12,17 Remaining questions include the longer-term efficacy and safety of these agents, as well as their efficacy and safety in additional populations, including geriatric patients, pediatric patients, or overweight but non-obese adults without comorbidities

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Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload