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5H, I), while overexpression of a codon-optimized L2HGDH (L2HGDH OPT ), which is resistant to the designed sgRNA, reverses this effect (Fig

Free radicals are unstable molecules that can damage cells and contribute to aging and various diseases

Cell Immunol 130:5208, PMID: 2208308 Yamauchi A, Bloom ET (1997) Control of cell cycle progression in human natural killer cells through redox regulation of expression and phosphorylation of retinoblastoma gene product protein

Our main interest is to understand the synthesis and export of GSH in liver cells and how intracellular metabolite balance is affected by oxidative stress

Estrogen levels exist in a high concentration pre-menopause, which decreases oxidative stress in the cardiovascular system

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