doi: 10.1111/cea.12860 40 KamuthachadLPisuttimarnPKasetthatTChetchotisakdPAnunnatsiriSSermswanRWet al
These central effects translate into substantial weight loss - typically 5%-15% of body weight with current GLP-1 RAs - which directly ameliorates hepatic steatosis by reducing adipose tissue mass, reducing hepatic free fatty acid influx, and improving insulin sensitivity
The active ingredient in Alli is known as orlistat
Gastro-oesophageal reflux is listed as a common side effect with some GLP-1 medications, affecting up to 1 in 10 people
On the other hand, reduced sexual function while taking a GLP-1 drug could occur due to reward signaling in the brain, according to Balazs
Even on GLP-1s, which help regulate insulin and blood sugar levels, your body will eventually adapt to the medication and your new, lower body weight