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GSH can be oxidized to its dimeric form, GSSG, in which way to scavenge reactive oxygen species and free radicals, protecting cells from oxidative stress and toxins 4

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For example, control experiments with millimolar GSH and a monothiol glutaredoxin mutant to exclude a monothiol mechanism often appear to be missing 40,41,87

This short exposure profile is consistent with its once-daily subcutaneous dosing in the clinical program

doi:10.1152/ajpendo.2002.282.1.E18 Mingrone G, Greco AV, Capristo E, et al