888 Ferroptosis in osteoporosis Osteoporosis is an age-related disease with a rising incidence in the elderly population, increasing the risk of fractures
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Protein post-translational modifications (PTMs), such as methylation, acetylation, phosphorylation, ubiquitination, and glycosylation, play crucial roles in epigenetic regulation by controlling protein activity, localization, folding, and interactions [5]
It exhibits this effect in the presence of the cuprizone toxin, which can cause neuron damage, including demyelination leading to the breakdown of myelin sheaths in the central or peripheral nervous system, without the need to reach the brain
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2025;17:e84705