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however, there is an increased risk for muscle toxicity

Cancer Res (2011) 71(7):245565

After a single subcutaneous dose of the GLP-1R agonist semgalutide (30 nmol/Kg), mice were given free access to water but no food or ethanol

& Klenerman, P

doi: 131

However, the relatively small differences with exendin-asp3 suggest that additional mechanisms beyond receptor trafficking may be involved in the blunted insulin secretory response with this compound