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Scientists at Duke-NUS Medical School in Singapore have uncovered a mechanism that leads to an advanced form of fatty liver disease - and it turns out that vitamin B12 and folic acid supplements could reverse this process
Adequate hydration supports kidney clearance, electrolyte balance, and may reduce headaches and constipationboth common GLP-1 side effects
The cost of a replacement vial is less than the cost of injecting degraded peptide that does not work or causes unexpected reactions
peaks during dose escalation, typically mild-moderate Diarrhea -- 10-20%, usually transient Constipation -- 8-15% Vomiting -- 5-15%, more frequent at higher doses Injection site reactions -- 5-10%, mild erythema and pruritus Decreased appetite -- 5-12%, related to mechanism of action Pancreatitis -- rare but monitored (as with all GLP-1/amylin agents) Gallbladder events -- cholelithiasis reported, consistent with rapid weight loss Trial data describes dose titration as central to tolerability -- the 16-week escalation protocol substantially reduced GI adverse events
87 A withdrawal reaction characterized by anxiety, insomnia, nausea, sweating, and increased pain has also been reported with abrupt discontinuation in patients taking it for pain
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