47 Visceral fat accumulation in patients with obesity causes a number of changes (oxidative stress, activation of the RAAS and gut dysbiosis), resulting in insulin resistance, increased vascular stiffness, T2D, dyslipidaemia, hypertension, coronary atherosclerosis and, ultimately, HFpEF
Its once-weekly dosing regimen has improved patient observation compared to daily injections, while its proven benefits in weight reduction and cardiovascular risk minimization have expanded its clinical use
Glucagon-like peptide 1 receptor agonists and heart failure: The need for further evidence generation and practice guidelines optimization
Pregnancy outcomes following maternal GLP-1 receptor agonist exposure: A systematic review and meta-analysis
I know I need nutrients
This is due to the gastric emptying delaying effect of short-acting agents, and the gastric emptying delaying effect of long-acting agents gradually decreases due to tachyphylaxis, thereby reducing the effect of postprandial glycemic control