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Upon conducting the histopathological examinations, our findings revealed significant indications of abnormal muscle development in the LMNA mutant transgenic fish, specifically the LMNA (L35P), LMNA (E358K), LMNA (R453W), and LMNA (A539V) variants

This work expands our understanding of GLP-1R activation and provides valuable insights into the potential application of ago-allosterism in drug discovery