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Notably, gene-expression studies have associated GHK-Cu with the modulation of thousands of genes tied to tissue remodeling and the inflammatory response, which is why it is studied as a foundational signal peptide in repair models

The peptide does not exist in the human body in this isolated form

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GHKCu modulates gene expression related to collagen synthesis, extracellular matrix production, antioxidant defense, and repair processes pathways central to skin regeneration and antiaging research

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