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The phase 2 trial included adults up to age 75, and older participants responded well to the drug

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Proc Natl Acad Sci U S A 111(29):107616 Chojnacki C et al (2023) Beneficial effect of increased tryptophan intake on its metabolism and mental state of the elderly

Protein identification and analysis The raw mass spectrometry data were processed using the Proteome Discoverer software (version 1.4, Thermo Fisher Scientific), as previously described 21

In people without diabetes, other hormonesincluding GLP-1, glucagon and amylinalso help with appetite, digestion and sugar balance

Evidence for longer-term effects beyond two years was more limited