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Cai Z, Xin J, Pollock DM, Pollock JS (2000) Shear stress-mediated NO production in inner medullary collecting duct cells

Its Phase 2/3 LIFT-AD Alzheimer's trial failed its primary endpoint, announced September 3, 2024 (global statistical test 0.08, P = .70)

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The peptide binds copper with extraordinarily high affinity (pK = 16.44), which is roughly 10 million times higher than other tripeptides and comparable to albumins copper binding

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